Researchers at Ogarev Mordovia State University have developed a promising new approach for treating fungal infections of the skin and nails.
The method is based on a natural photosensitizer derived from Sosnowsky’s hogweed extract, combined with a portable device that integrates both diagnosis and therapy. During treatment, ultraviolet light activates naturally occurring furanocoumarins, which selectively destroy fungal cells without damaging healthy tissue.
One of the key advantages of this innovation is its ability to overcome antifungal resistance — a major challenge in modern treatment. According to the researchers, this mechanism is effective against both natural and acquired resistance, with no risk of resistance developing over time.
The therapy is also localized, minimizing systemic side effects. The treatment is applied directly to the affected area using a roller applicator, followed by targeted UV exposure, ensuring only infected tissue is treated.
Additionally, the technology enables precise diagnosis: many fungal pathogens fluoresce under UV light, helping to clearly define the affected area.
The research team has successfully completed in vitro studies, with the next stage involving testing on laboratory animals.
This development highlights the university’s growing contribution to biomedical innovation and its capacity to create practical, globally relevant healthcare solutions.